Yaoxue Xuebao

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Yaoxue Xuebao

Yaoxue Xuebao (ISSN:0513-4870) is a monthly peer-reviewed scopus-indexed journal from 1960, from 1962 to 1966, from 1979 to Present. The publisher of this journal is Chinese Pharmaceutical Association. Yaoxue Xuebao committed to gathering and disseminating excellent research achievements. The journal welcomes all kind of research/review/abstract papers regarding Pharmacology, Toxicology and Pharmaceutics, General Pharmacology and Toxicology and Pharmaceutics Biochemistry, Genetics and Molecular Biology and Molecular Medicine and so on.

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Yaoxue Xuebao

YX-18-11-2024-2105
| Yaoxue Xuebao (ISSN:0513-4870)

Comparative analysis of chemical constituents in hawthorn leaves from different sources

We identified and analyzed the components and chemical constituents of hawthorn leaves of Crataegus pinnatifida Bge. (wild) and C. pinnatifida Bge. var major NE Br (cultivated) by using ultra high-performance liquid chromatography and quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF/MSE) combined with UNIFI data analysis platform and multivariate statistics. Fifty-eight chemical compounds were identified, including organic acids, flavonoids, triterpenoic acids, monoterpenes and sesquiterpenoids; among them, terpenoid content was the most abundant. Principal component analysis (PCA)

Research progress of febuxostat derivatives as xanthine oxidase inhibitors

Febuxostat, as a xanthine oxidase inhibitor, is a classic anti-gout drug with significant therapeutic effects and good tolerability. The structures of febuxostat and its derivatives can be divided into two parts: a substituted phenyl ring and a five-membered or six-membered heterocyclic ring with a carboxyl substitution. This paper reviewed the research progress of febuxostat derivatives in recent ten years and classified the structure-activity relationships of various febuxostat derivatives. Exploring the action mechanisms and structure-activity relationships of xanthine oxidase inhibitors

Research Progress of Human Gut Microbiome for Forensic Personal Characterization

Human intestinal tract accommodates the most varieties and quantity of microbes in human body, establishing the colonies of bacteria, viruses, fungi, archaea and eukaryotes that have come into being the so-called human gut microbiome (HGM). Evidently, HGM is characteristic of enormous amount of microbes, long-duration stability and liability of individual specificity, hence making it promising to arise as a novel biomarker for forensic personal identification. Factually, the explosion of microbiomics research occurred along with the availability of high-throughput sequencing in the last dec

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Yaoxue Xuebao

Yaoxue Xuebao

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Yaoxue Xuebao

Comparative analysis of chemical constituents in hawthorn leaves from different sources

Research progress of febuxostat derivatives as xanthine oxidase inhibitors

Research Progress of Human Gut Microbiome for Forensic Personal Characterization

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