Yaoxue Xuebao

Submission On

( Vol 60 , Issue 04 ) |

27 Dec 2025
Day
Hour
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Publish On

( Vol 60 , Issue 04 ) |

31 Dec 2025
Scopus Indexed (2026) scopus
ABCD Indexed (2025) scopus
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Yaoxue Xuebao

Yaoxue Xuebao (ISSN:0513-4870) is a monthly peer-reviewed scopus-indexed journal from 1960, from 1962 to 1966, from 1979 to Present. The publisher of this journal is Chinese Pharmaceutical Association. Yaoxue Xuebao committed to gathering and disseminating excellent research achievements. The journal welcomes all kind of research/review/abstract papers regarding Pharmacology, Toxicology and Pharmaceutics, General Pharmacology and Toxicology and Pharmaceutics Biochemistry, Genetics and Molecular Biology and Molecular Medicine and so on.

Aim And Scope

Yaoxue Xuebao

Pharmacology

Toxicology and Pharmaceutics

General Pharmacology

Toxicology and Pharmaceutics Biochemistry

Genetics and Molecular Biology

Molecular Medicine

Latest Journal

Yaoxue Xuebao

  • YX-18-11-2024-2138
  • | Yaoxue Xuebao (ISSN:0513-4870)

Analysis of the mechanisms of Guanxinning Tablet for antithrombotic and microthrombotic effects caused by COVID-19 based on network pharmacology

Chuanxiong rhizoma (CX) has been utilized for centuries as a traditional herb to treat blood stasis syndromes. However, the pharmacological mechanisms are still not completely revealed. This research was aimed at exploring the molecular mechanisms of CX treatment for thrombosis. Network pharmacology was used to predict the potential anti-thrombosis mechanism after correlating the targets of active components with targets of thrombosis. Furthermore, we verified the mechanism of using CX to treat thrombosis via molecular docking and in vitro experiments. Network pharmacology results showed th

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  • YX-18-11-2024-2137
  • | Yaoxue Xuebao (ISSN:0513-4870)

The effect and mechanism of Lycium barbarum leaves on D-galactose-induced cataract in rats based on metabolomics

The aim of this study was to investigate the effects of Lycium barbarum Polysaccharide (LBP) on alcohol-induced liver damage in rats. A total of 36 rats were divided into control, ethanol and ethanol + LBP groups. Rats in the ethanol group were fed 7 g ethanol/kg body weight by gastric infusion, three times a day, for 30 consecutive days, while rats in the control group received the same volume of physiological saline instead of ethanol, and rats in ethanol + LBP group were fed both ethanol (7 g/kg body weight) and LBP (300 mg/Kg body weight/day). Alcoholic liver injury was examined by seru

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  • YX-18-11-2024-2136
  • | Yaoxue Xuebao (ISSN:0513-4870)

Chemical constituents of dichloromethane extract from the stems of Ephedra intermedia

Six new compounds, (7R,8S,8′R)-balanophorone (1), (7′S,8′R,8R)-yunnanensin A (2), (3S)-thunberginol C (3), (8R,8′R)-maninsigin B (4), (7S,8R)-4,7,8-dihydroxy-9,9-dimethyl-chroman (5), and 4-hydroxy-1-(4-hydroxy-3-methoxyphenyl)butan-1-one (6), along with eight known compounds (7–14), were isolated from the herbaceous stems of Ephedra intermedia Schrenket C. A. Meyer. Their structures were elucidated based on their spectroscopic (MS, NMR, IR, and UV) data, and their absolute configurations were determined by comparing their calculated and experimental electronic

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  • YX-18-11-2024-2135
  • | Yaoxue Xuebao (ISSN:0513-4870)

Two new lanostane triterpenoids from Ganoderma applanatum

Our previous research has shown that lanostane triterpenoids from Ganoderma applanatum exhibit significant anti-adipogenesis effects. In order to obtain more structurally diverse lanostane triterpenoids to establish a structure–activity relationship, we continued the study of lanostane triterpenoids from the fruiting bodies of G. applanatum, and forty highly oxygenated lanostane-type triterpenoinds (1–40), including sixteen new compounds (1–16), were isolated. Their structures were elucidated using NMR spectra, X-ray crystallographic analysis, and Mosher’s method. In

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  • YX-18-11-2024-2134
  • | Yaoxue Xuebao (ISSN:0513-4870)

Recent advances of conditionally active antibodies

Immune checkpoints and other immunoregulatory targets can be difficult to precisely target due to expression on non-tumor immune cells critical to maintaining immune homeostasis in healthy tissues. On-target/off-tumor binding of therapeutics results in significant pharmacokinetic and pharmacodynamic problems. Target-mediated drug disposition (TMDD) significantly limits effective intratumoral drug levels and adversely affects anti-tumor efficacy. Target engagement outside the tumor environment may lead to severe immune-related adverse events (irAEs), resulting in a narrowing of the therapeut

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The publisher of this journal is Chinese Pharmaceutical Association. Yaoxue Xuebao committed to gathering and disseminating excellent research achievements.

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